Monday, June 30, 2008

Anxiety Management With Prescription BuSpar: Don't Worry, Be Happy


We’ve all had one of those weeks: the washing machine overflows, the dog forgets his housetraining and the toddler her toilet training, the boss is going through a divorce and making everyone miserable. And you feel like you just don’t know how to handle it all.

Anxiety is, unfortunately, an inevitable part of modern life. But when anxiety prevents you from engaging in day-to-day activity or trying anything new, it may be time to see your doctor for anti-anxiety help.

What causes anxiety?

Anxiety is the feeling caused by the release of stress hormones and brain chemicals which help us fight for our lives or flee from danger. In our evolutionary past, bursts of stress hormones may have helped give us a boost when running away from large animals with big teeth! And believe it or not, in the right situation, these hormones can be a big help in day-to-day activities. Mild tension before giving a presentation can help you do your best. A burst of brain chemicals can help speed your reaction time when you see a pedestrian dashing in front of your car and can save someone’s life!

When anxiety becomes a constant companion in our lives, we may start having symptoms of anxiety when we think about anything - work, marriage, children, even going to the grocery store. The symptoms include muscle tension, sweating, nausea or “butterflies,” clammy hands, difficulty swallowing, jumpiness, stomach distress.

If these symptoms have become part of your everyday life, it may be time to talk with your doctor about an anti-anxiety medication like BuSpar.

But I’d rather be anxious than spacey!

You may remember the days where anxiety was treated with heavy-duty drugs that could tranquilize a bad-tempered elephant! But as scientists have learned more about the biology of anxiety, anxiety management has become more sophisticated, helping your mood without making you a zombie. You won’t turn into a Stepford wife. Instead, you’ll go back to reacting the way you used to, both to happy events and anxiety-provoking situations.

BuSpar works gently by affecting your feelings over the course of a few weeks. Most people begin getting relief over that time period and can start getting back to living their lives.

While you don’t have to worry about walking around in a haze, many people do feel some dizziness or drowsiness when they are first getting used to BuSpar. You may want to avoid driving or operating heavy machinery until your body has adjusted to the medication.

Sounds great! Let’s head to the drug store.

Well, not just yet. BuSpar is a prescription drug, and you’ll want to check a few things out with your doctor before she gives you a prescription.

If you’re taking monoamine oxidase (MAO) inhibitors (a kind of anti-depressant) or certain other drugs, have ever had an allergic reaction to mood-altering drugs, or have severe kidney or liver damage, this may not be the right drug for you.

Lastly, alcohol can have a major impact on how your body responds to BuSpar, so you may want to skip the champagne in favor of a pancake brunch when celebrating your anxiety-free life!

You can buy Buspar here

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Syria's weblog

Complementary and Alternative Treatments for Urinary Incontinence


Treatment for incontinence depends on what is causing the condition. For example, if a prostate gland problem is the cause, treatment for that condition can cure incontinence. In severe cases, an artificial sphincter, which allows you to control its open and closed settings, can be surgically implanted. Collagen injection therapy-where in collagen is injected into the external bladder to add bulk to the urethra is effective in some cases for women with sphincter deficiency and for men who experience urinary stress incontinence after prostate surgery. Medication also may be prescribed to treat incontinence; commonly prescribed drugs are anticholinergic agents (Pro Banthene), alpha-adrenergic agonist drugs, tricyclic antidepressant drugs, and antispasmodics (Bentyl, Ditropan, and Urispas). Postmeonpausal women with stress incontinence may benefit from estrogen either orally or by applying a cream to the vagina.

Complementary and Alternative Treatments

Ayurvedic Medicine

Ayurveda views incontinence as a vata disorder that's caused by a weak bladder sphincter. Your Ayurvedic practitioner may recommend taking an Indian herbal blend containing ashwagandha and also may suggest eliminating or reducing your intake of alcohol and coffee and other caffeine-containing foods, which intensify the urge to urinate as well.

If symptoms persist, see your doctor for evaluation and assistance.

Bodywork and Somatic Practices

Oriental bodywork, reflexology, massage, Therapeutic Touch, Reiki, polarity therapy, and CranioSacral Therapy are helpful first options.

Traditional Chinese Medicine

Acupuncture Chinese medical experts believe that incontinence is caused by a lack of energy in the kidney and spleen and their related meridians. To combat this imbalance, they work on the points that correspond to these areas and to the bladder.

Acupressure Points that may be focused on during an acupressure session to treat incontinence are Conception Vessel 2, Spleen 6, and related auricular points.

Chinese Herbal Therapy Herbs may be given to help tone the kidney and spleen and to strengthen bladder functions.

Yoga and Meditation

Exercise is always beneficial for strengthening muscles, including those of the bladder and surrounding areas. Try these easy yoga exercises several times daily to combat incontinence: Ashwini Mudra and Stomach Lock. Consult a trained practitioner for proper technique. Avoid these poses if you're pregnant.

You can buy Urispas here

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Old Grumpy Dwarf's weblog

Epileptic Seizure Solution


Being a very unpredictable disease, epilepsy frequently rules the lives of those attacked by it. The solitary way to maintain control over symptoms is by using assorted combinations of anti-convulsive drugs and developing a well-balanced style of living that keeps excesses of all kinds away.

Mysoline, is an anti-convulsive drug that stops seizures triggered by epilepsy. This form of long-term treatment can be taken for an indefinite period of time. However long you keep taking it, be absolutely sure a close contact with your doctor is maintained for a professional monitoring of your condition.

Treatment Specifics

This medication should be administered as suspension or capsules, and quantity depends on the intensity of the problem, body weight and age. If you choose Mysoline in liquid form, keep it in a dark location and vigorously shake the bottle prior to every usage to ascertain you get the accurate amount.

If you miss a dose, take it as soon as possible. If it is within 1 hour of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Warnings

The only health circumstance that is totally mismated is porphyria, an inherited metabolic disorder.

At the conclusion of treatment, never discontinue taking this medication abruptly, as this may contribute to stronger seizures than you've experienced previously. Withdrawal must be a gradual process.

Taking into consideration the fact that this drug is, for the most part, administered for an eminently

long period of time, intermittent blood tests are imperative to maintain an accurate view of your health condition, and to inhibit any possible system decline in quality.

Beware of drug interactions

Prior to beginning any new drug therapy, make sure it doesn't interject with this medication.Or you risk to jeopardise the effectiveness of either. Medications that are susceptible to Mysoline incumbrance include: estrogen based oral contraceptives, certain antibiotics, blood-thinning drugs, anti-depressants and steroidal drugs

On that account, try to abstain from all alcoholic drinks while using this medication. In order to circumvent possible unwanted side effects, it is important to inform your health care provider on the use of this drug.

There are an abundance of other drugs that can be safely mixed with Mysoline without triggering any negative effects. Your doctor is the most qualified person to talk to when needing to interpret other assorted health troubles that inevitably appear.

Use this medication exactly as prescribed. Do not change from one manufacturer's product to another without consulting your doctor.

Continue taking Mysoline even if you feel well. Do not miss any doses.

Mysoline gives you the effectiveness of phenobarbital plus additional protection. A patient whose seizures have not been controlled by phenobarbital may have better results from Mysoline.

study in children-which also included Depakote (valproate)-focused on the rate of side effects. Only 8% of the children who were given Mysoline had to stop taking it because of side effects. Phenobarbital, which can be an excellent medication, often is avoided in children because of the possibility of mental slowing. By using Mysoline alone, children can enjoy many of the same benefits while avoiding this problem because the amount of phenobarbital produced by breaking down the Mysoline is low.

It is important to remember that no single combination of antiepileptic medications is perfect for everyone. Sometimes, a series of combinations must be tried before finding what is best for the individual patient.

You can buy Mysoline here

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Archus's weblog

Weight Loss - Ways You Can Lose Weight Naturally and Easily


1. Portions - Portion control is possibly one of the most effective ways to lose

weight fast and without frustration. Reduce your portions - just eat half of what

is on your plate, either at home or in a restaurant and keep the remainder for

next time.

2. Go meatless - Take meat off the menu for a few meals during the week.

Substitute with soy proteins or legumes or kidney beans. Even mushrooms like

portobello are great burger substitutes. Try veggie burgers and falafel.

3. Spicy food - Spiking your food with spices not only makes them tastier but

healthier as well. Furthermore spices like hot peppers have been shown to raise

the metabolic rate by almost 50% for a few hours after meals.

4. Everyday exercise - Take the stairs whenever possible. Park your car furthest

from the store. Take a walk to the water cooler once every hour (you'll also get 8

cups of water that way!). Stretch whenever possible - whether standing or sitting.

Even standing straight for 5-10 minutes against the wall helps.

5. Drink water - Drinking adequate water helps to detoxify the body, encourages

metabolism and also keeps hunger pangs at bay.

6. Alternative dinners - Try having cereal & milk for dinner ...or pita &

hummus...or fruit & yogurt or a big meatless salad. Anything that is light yet

filling.

7. Herbal Supplements - Try herbal ayurvedic supplements that have no side effects

like Ayurslim. It is a totally herbal composition of herbs like Garcinia, Gymnema,

Guggul, Haritaki, Medhika - all proven fat burning, cholesterol lowering & glucose

metabolizing agents.

You can buy AyurSlim here

.
Kestra's weblog

Sunday, June 29, 2008

Side Effects of Some Drugs that Are Lowering Blood Pressure(part One)


Lowering blood pressure is a condition that is below the normal expected for an individual in a given environment. Blood pressure differs deeply with activity, age, medications, and underlying medical conditions

Some of the Drugs have some side effects that can cause lower blood pressure include blood pressure drugs, diuretics (water pills), heart medications (especially calcium antagonists-nifedipine/Procardia, beta blockers-propranolol/Inderal and others), depression medications (such as amitriptylene/Elavil), and alcohol.

Diuretics — diuretics are a big evil of lower blood pressure. It could cause lack of potassium in your body. Usually after taking diuretics, patient may suffer from weakness, leg cramps, or being tiredness however, it is not permanent. A patient can avoid these problems by taking some potassium tablets with diuretics. Diuretics such as amiloride (Midamar), spironolactone (Aldactone) or triamterene (Dyrenium) are called "potassium sparing" agents and provide equal of amount of potassium to your body. A lower blood pressure patient with diabetes can have some problems with diuretics. It may increase the blood sugar level. So, it is recommended to take permission from doctor before taking it.

Beta-blockers — patients of lower blood pressure feel insomnia, cold hands and feet, tiredness or depression, a slow heartbeat or symptoms of asthma after taking Beta-blockers. Patients of diabetes need to care while taking this medicine.

ACE inhibitors — a required amount of ACE inhibitors not effect badly to lower blood pressure patient but the drugs, such as captopril (Capoten), enalapril (Vasotec), lisinopril (Zestril or Prinivil), may cause a skin rash; loss of taste; a chronic dry, hacking cough; and in rare instances, kidney damage.

Angiotensin II receptor blockers — another evil for the patients of lower blood pressure. A patient may feel occasional faintness, so take care, and ask your doctor before taking the drug.

Calcium channel blockers —lower blood pressure patient may suffer from palpitations, swollen ankles, constipation, headache, or dizziness with this medicine. Form of Calcium channel blockers are Diltiazem (Cardizem), nicardipine (Cardene), Nifedipine (Procardia) and verapamil (Calan or Isoptin) which is injurious in lower blood pressure.

These side effects will continue in the next article "Side effects of some drugs that are Lowering Blood Pressure(part two)"

You can buy Isoptin here

.
MadandAngry's weblog

Breast Augmentation - Is Bigger Really Better?


So, you're thinking about breast augmentation? There are certainly a lot of things to consider before you take the plunge. Ultimately, your final breast size will be determined by the limitations of your body, but you will want to do some research into what makes you most comfortable.

Some women long for large, over the top, breasts. Others could care less what their breast size is. Most women fall somewhere in the middle. If you're on the smaller size and are thinking about going up a cup size or two, you're not alone. Studies show that millions of American women wish they were just a little bit larger in the chest.

Before you commit to an implant size, try some larger breasts on for size. By this, we mean purchase a couple of bras with cup sizes a size or two larger and stuff them. Wear each one for a few days so that you can get a feel for what your new breasts will look like. This is an important step in determining how large you should go. For most women, going up just one cup size does the trick. For others, they really like the idea of those double-D's.

A board certified plastic surgeon is a great resource for helping you select the best implant size for you. Your plastic surgeon is most concerned with making you happy while making sure that your chosen implants are the most proportionate for your body size. Bring those bras that you bought for your research along with you to your visit with your plastic surgeon and you'll be able to place an actual implant into the bra to give you a pretty realistic idea of how your new breasts will look and feel.

Your plastic surgeon will help you determine the size that is best for you based on your body size, the placement of your natural breasts, the thickness of the skin on your chest, and the fat content of your upper body. He or she is also the best resource for information on whether saline or silicone implants best suit your needs and lifestyle.

You can buy Breast Augmentation here

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Arkaig_Roe's weblog

Friday, June 27, 2008

Are Medications for the Treatment of Enlarged Prostate (Benign ...


Alpha adrenergic receptor blocker medications, including doxazosin (Cardura), prazosin (Minipress), alfuzosin (Uroxatral), and terazosin (Hytrin), cause a relaxation of prostate smooth muscle and increase urine flow (Lepor et al 1996; McConnell et al 2003). The FDA has approved all of these medications for the treatment of BPH, with the exception of Minipress. Minipress is a medication that has been on the market for the treatment of hypertension for many years; your doctor has the right to prescribe it for you "off label" for the treatment of BPH if he or she thinks it is indicated. There are no current plans to obtain an indication for Minipress for the treatment of BPH, since it has been off patent for many years. All of the alpha adrenergic receptor blocker medications have similar side effects including dizziness, postural hypotension, and fatigue. The potential benefit from relief of BPH symptoms is usually worth the side effects of these medications. However, Uroxatral should not be used in patients with liver problems and causes cardiac effects (lengthening of the Q-T interval).

Tamsulosin (Flomax) is a selective blocker of the ±-1A adrenergic receptor that has fewer side effects than the other alpha-blockers because it is more selective to the ±-1A adrenergic receptor than the other drugs reviewed above. The other alpha blockers block adrenergic receptors in both the heart and the brain as well as in the prostate. For this reason they can block the smooth muscles in the blood vessels in these areas and cause the blood vessels to dilate. This changes blood flow in the brain, with associated dizziness, fatigue, or the possibility of passing out if you stand up too quickly (postural hypotension). Since Flomax is more specific to the adrenergic receptors in the prostate, it has fewer of these side effects.

5±-reductase inhibitors include drugs like finasteride (Proscar). One of the most important factors contributing to BPH is the male hormone dihydrotestosterone (DHT). DHT normally stimulates prostate tissue in adolescent males, which leads to the ability to produce semen and therefore become fertile. In later age, however, DHT can stimulate prostate tissue in a counter-productive way. Proscar inhibits the enzyme responsible for the conversion of testosterone to DHT, 5±-reductase, thereby reducing DHT levels as much as 80%. This is associated with a decrease in prostate volume of 20%, since this hormone stimulates prostate tissue growth. Side effects include decreased libido, impotence and ejaculatory disorder. Dutasteride (Duagen) blocks both types 1 and 2 5±-reductase and has a similar side effect profile as finasteride.

In the PROscar Safety Plus Efficacy Canadian Two Year Study (PROSPECT), 613 men with moderate BPH symptoms were started on a two year treatment course with Proscar or placebo (Nickel et al 1996). Finasteride resulted in a statistically significant reduction in symptom scores compared to placebo, with a baseline score of 15.8 the difference between finasteride and placebo was only 0.4, not a very big difference. There was about a 10% increase in urinary flow rates. Over twice as many (15.8%) of finasteride patients developed impotence as patients on placebo (6.3%). In a study comparing finasteride to the alpha blocker terazosin and placebo, 1229 were randomized to blinded treatment for one year. Change in symptom scores were 2.6 for placebo, 3.2 for finasteride, 6.1 for terazosin, and 6.2 for terazosin and finasteride.(Lepor et al 1996) Similar improvements were seen with urine flow, with greater increases in urine flow for terazosin. Finasteride was no better than placebo, while terazosin was statistically significantly better than both finasteride and placebo. Impotence was higher with finasteride (9%) than placebo (5%) or terazosin (6%). Another study looking at the long term effects of these drugs studied 3047 patients for five years on placebo, doxazosin (alpha blocker), finasteride, or combination therapy. The outcome was a four point increase in BPH symptom score, urinary retention or incontinence. Doxazosin reduced progression by 39% and finasteride by 34% compared to placebo (both statistically significant) (McConnell et al 2003). Combination therapy was even better (66% reduction) and was associated with a reduction in the need for surgery, as was finasteride alone.

Based on these findings I recommend the use of the alpha blockers initially (doxazosin (Cardura), prazosin (Minipress), alfuzosin (Uroxatral), and terazosin (Hytrin) and Flomax) with addition of Proscar or Duagen depending on symptom response and side effects. Talk it over with your doctor.

Lepor H, Williford WO, Barry MJ (1996): The efficacy of terazosin, finasteride, or both in benign prostatic hyperplasia. Veterans Affairs Cooperative Studies Benign Prostatic Hyperplasia Study Group. New England Journal of Medicine 335:533-539.

McConnell JD, Roehrborn CG, Bautista OM (2003): The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia. New England Journal of Medicine 349:2387-2398.

Nickel JC, Fradet Y, Boake RC, Pommerville PJ, Perreault JP, Afridi SK (1996): Efficacy and safety of finasteride therapy for benign prostatic hyperplasia: results of a 2-year randomized controlled trial (the PROSPECT study). PROscar Safety Plus Efficacy Canadian Two year Study. Canadian Medical Association Journal 348:602-606.

You can buy Proscar here

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enderhelpme's weblog

Enhance Your Sexual Pleasure With the Help of Food


Sex is something that both men and women have been so preoccupied about even during the ancient times. However, when it comes to aphrodisiacs and sexual stimulants, men usually have the upper lead. In Ancient China, men are willing to pay huge sums of money in order to acquire exotic aphrodisiacs, such as balls of tigers, bones of cobras and even dried and powdered seahorses.

Nowadays, the idea that food from animals and plants can make men more virile is still very popular. Surf the Net and you will see many online stores selling out-of-this-world contraptions and potions that promise to boost men's libido. However, only a few items or articles are available for women who are interested in increasing their sexual pleasure and arousal.

If you are one of those women who want to make use of natural ingredients to improve your sexual desire and arousal, read on and learn that some things you find in your kitchen or pantry can actually help whet your appetite for sex.

Gingko Biloba

Quite a number of studies have shown that Gingko Biloba, also called the tree of life, improves blood circulation. In fact, many believe that the leaves of this tree can help your brain function better. Its ability to promote good circulation is also what makes this herb a good aphrodisiac. With the help of Gingko, there is a marked improvement in the flow of blood to the genital areas, making women easily aroused and satisfied.

Safed Moosli

This tuber plant, whose scientific name is Chlorophytum Borivilianum, has been used for years to help treat various ailments. Nowadays, however, it is considered as a potent sex tonic, particularly in Asian countries. According to Ayurveda tradition, this plant helps rejuvenate the reproductive system of both men and women.

Chocolate

Most probably, men do not know where the tradition of giving women chocolates as a sign of love originated. Probably, the first few men who offered bars and boxes of chocolate to women realized that this bittersweet treat can improve the mood of even the most iron-hearted women.

Chocolate contains components that increase the production of serotonin in the brain. This substance is responsible for pleasure and relaxation. They say that dark chocolate is more potent in making women feel good. Men out there know that a woman who is happy is more willing and open for the possibility of being intimate in the bedroom.

Arginine

At first mention of Arginine, you probably are thinking that this substance is quite difficult to have. In reality, however, Arginine is abundant in the food you have inside your refrigerator or pantry. This amino acid is actually found in cheese, milk, meat, nuts, coconut milk and eggs. This substance is known to help enhance sensation of the clitoris, reduce dryness of the vagina, boost desire for intimacy and help in reaching climax or orgasm. What's more, Arginine is also vital in slowing down the process of aging.

Pine Nuts

Who would ever think that these small nuts could be used as a natural aphrodisiac for women? The birth rate in the Himalayan region, where pine nuts are quite popular, could be an indication that these lowly nuts can be very effective in making women more sexually active. Kidding aside, scientists believe that the protein content of pine nuts might be the one responsible for improving sex hormone levels in women. This might explain why these nuts are considered as potent aphrodisiac.

Damiana

A lot of husbands and partners will agree that women who are in the verge of menopause suddenly don't find having sex attractive. Good thing there is Damiana, a South American shrub, which is known for stimulating female sex organs and toning the membranes of the reproductive organs. Majority of women who took supplements that contain Damiana, such as Menersa, claimed that their sexual interest and pleasure were enhanced even during menopause.

You can buy Female Sexual Tonic here

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Khaoz's weblog

Thursday, June 26, 2008

Are You Only One Infomercial Away From Perfect Health?


You've seen the late-night infomercials that claim all you have to do is swallow a pill and you will look like a Hollywood Star or be cured of any disease or lose hundreds of pounds in a week just sitting in your Lazy-boy. Of course this is preposterous but boy oh boy are they making money.

When it comes to infomercials regarding weight management products or supplements, the pattern is rather predictable. Have a token medical professional for credibility, establish a problem, create fear and then graciously provide the solution. Infomercials are typically 28 minutes long and are really four, seven-minute shows repeated.

One of the more popular infomercials that flooded the airwaves a few years ago was selling the nutrient Coral Calcium. Coral calcium is a form of calcium purported to be taken from ocean reefs. The first objective of the infomercial is to make you believe they have uncovered a revelation in longevity. Next they explain that they have figured out a way to extract this calcium from the sea.

Then they proceed to tell you that this miracle nutrient will make you alkaline. Next, they talk about how disease cannot live in an alkaline environment. Yes, even cancer cells. They tell you how this particular form of calcium is so unique it increases bone density like no other calcium. "Look at sea creatures," they clamor, "do they die from our diseases?(naturally implying that the fish eat the reefs to get calcium). So after building their case as to why an alkaline environment will prevent any disease from living, they proceed to tell you how their calcium will help you achieve this. Conclusion: Coral calcium prevents and cures cancer as well as all other diseases.

How prevalent is this nonsense. But the fact is, millions of people buy into this "miracle-nutrient" mentality. For example, I was sitting with a high-ranking official of a large bank, a very bright and well-educated man. As we were pouring through financial data, he stopped and gave me a "can-we-change-the-subject-for-a-minute" look. I gave him a "sure-we-can" look and he proceeded to tell me the following. '"That coral calcium that you see on T.V., does it really cure cancer?I asked him point blank,"What do you think?"? Do you think Coral Calcium can cure cancer?" He said sheepishly, "I guess it is silly to think that one mineral is the answer to all of America's health ills." I told the banker that indeed he was right.

Health is never about one nutrient or even thirty nutrients for that matter. True health is about following some basic principles and supporting the body on a cellular level with nutrient-dense food. It is about exercising. It is about eliminating toxins. It is about emotional health. It is about drinking water and breathing correctly.

Infomercials exist and will continue to exist because people want to believe that they can accomplish better health or weight loss or a body like Chuck Norris without having to dramatically change their lifestyle. Earlier this morning, I saw an infomercial claiming that you can lose all the weight you want without changing a thing in your life. Just swallow the pill, eat what you want, continue sitting on the couch all day and you will look like a supermodel or professional athlete. Pure malarkey.

Improving or regaining your health is a process. It does not happen instantaneously no matter what you hear. The process does not have to be one of denial or cataclysmic changes. One simply needs to acquire the right information about their body and start making some changes on a daily basis. But to take a journey you must start a journey.

Next time you flip the channel and land on a health infomercial, use your God-given common sense. If it sounds too good to be true... well, you know the rest.

You can buy Coral Calcium here

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Praestat's weblog

Calcium Carbonate Source


Calcium carbonate is only one of the many compounds used in making calcium supplements. Calcium carbonate is an alkaline-based salt. That is why it is known to control acidity in the stomach. It also requires an acidic environment to get absorbed, and therefore recommended by doctors to be taken after meals.

It has been found recently that coral calcium is the most effective calcium carbonate source. This salt is obtained from fossilized coral reefs above sea level. It is pure, refined and contains many other minerals in addition to adequate amounts of calcium. It is good for health because it not only helps in overcoming calcium deficiency but also treats many illnesses including depression, obesity, high cholesterol, and high blood pressure.

This calcium carbonate source is now used in making high-quality calcium supplements. Coral calcium harvested from the island of Okinawa in Japan has been found to be the most beneficial form of this salt in terms of improving health and preventing many degenerative diseases. Japanese people who drink water containing coral calcium are at reduced risk of developing coronary heart disease and many types of cancer.

You can now buy these supplements easily as they are available at many online stores. Recommended dosage of any calcium carbonate source is 2 to 3 tablets a day after every meal. These tablets help in proper digestion of food and are easily absorbed by the bloodstream. People who are deficient of calcium are especially advised to increase their calcium intake through diet as well as calcium tablets.

An average healthy man should consume up to 1200 mg of calcium daily. Post menopausal women are at high risk of developing osteoporosis or bone disease, and therefore they should consume at least 1500 mg of calcium daily. At this age it is not possible to receive this amount solely from food. Calcium supplements are very useful in these situations and they should also be used by people who are allergic to milk and other dairy products.

Liquid coral calcium supplements are also available on the market. They are ideal to be used by elderly people and children under the age of 10. In addition to being a rich calcium carbonate source, these supplements also contain vitamin D, K2 and certain other minerals like magnesium, sodium and potassium. These minerals are important for overall health and also help in calcium absorption.

You can buy Calcium Carbonate here

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Telantaa's weblog

Sleep Well in Your Green Bedroom


We all know about the benefits of eating organic foods and using eco-friendly free cleaners and other household items, but now this toxin-free existence has extended into other areas of the house. Apparently a tidy, relatively dust-free bedroom just doesn't cut it anymore in today's chemical ridden society.

How green is your rug? Natural products such as jute or wool are the most desirable.

Your bedroom furniture may be oozing toxic gases. Anything composed of particle board or paneling and left unsealed, can emit formaldehyde and has the potential to cause difficulty in breathing, watery eyes, or allergies. Extreme levels have been known to cause cancer in animals and humans.

When you're painting your walls, look for a low VOC brand that contains less toxins. A good rule of thumb is, the stronger the paint smell after you put it on the wall, the higher the level of toxicity.

How many of us are sleeping on an organic bed? An organic bed emits no toxic chemicals and provides a healthy sleep environment.

Most traditional mattresses are made with fire retardant chemicals which seep out, only to be absorbed by our pores and lungs while we are sleeping. After ingesting various chemicals throughout our average day, it gives our bodies a much needed rest if we omit these toxins from our sleeping hours. This is especially true when you consider that people spend about one third of their life in bed.

Some of the common toxins emitted during sleep include:


  • Formaldehyde, a chemical which is used in many adhesives and can cause eye and throat irritation and headaches.

  • Carcinogenic flame-retardants (known as PBDE’s), many of which are banned in Europe and some U.S. States.

  • Decabromodiphenyl Oxide, a brominated flame retardant now being found in women's breast milk.



Here are a few of the green features in organic bedding and mattresses:


  • Natural latex cores wrapped in a natural flame retardant such as cotton or wool

  • Emission-free mattresses that contain neither glue nor adhesives (these can emit toxic fumes for the first 2-3 years)

  • Natural fiber bedding that not only breathes, but naturally resists dust mites
  • Any cotton material used in the production of the bedding should be unbleached. Traditional cotton is not an acceptable choice due to its exposure to large amounts of pesticides and fertilizers prior to harvesting.

  • No PBDE’s (fire retardants)

  • Hypo-allergenic

  • Made in a chemical-free manufacturing plant



Various affordable green mattress retailers include IKEA, Cozypure, Gaiam Greensleep/Vimala and EcoChoices.

You can buy SleepWell (Herbal XANAX) here

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Boogs's weblog

Weight Loss - Ways You Can Lose Weight Naturally and Easily


1. Portions - Portion control is possibly one of the most effective ways to lose

weight fast and without frustration. Reduce your portions - just eat half of what

is on your plate, either at home or in a restaurant and keep the remainder for

next time.

2. Go meatless - Take meat off the menu for a few meals during the week.

Substitute with soy proteins or legumes or kidney beans. Even mushrooms like

portobello are great burger substitutes. Try veggie burgers and falafel.

3. Spicy food - Spiking your food with spices not only makes them tastier but

healthier as well. Furthermore spices like hot peppers have been shown to raise

the metabolic rate by almost 50% for a few hours after meals.

4. Everyday exercise - Take the stairs whenever possible. Park your car furthest

from the store. Take a walk to the water cooler once every hour (you'll also get 8

cups of water that way!). Stretch whenever possible - whether standing or sitting.

Even standing straight for 5-10 minutes against the wall helps.

5. Drink water - Drinking adequate water helps to detoxify the body, encourages

metabolism and also keeps hunger pangs at bay.

6. Alternative dinners - Try having cereal & milk for dinner ...or pita &

hummus...or fruit & yogurt or a big meatless salad. Anything that is light yet

filling.

7. Herbal Supplements - Try herbal ayurvedic supplements that have no side effects

like Ayurslim. It is a totally herbal composition of herbs like Garcinia, Gymnema,

Guggul, Haritaki, Medhika - all proven fat burning, cholesterol lowering & glucose

metabolizing agents.

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Wednesday, June 25, 2008

Medication Treatment of Hypertension - Which Drugs are Best?


Drugs used in the treatment of hypertension include thiazide diuretics, beta blockers, angiotensin converting enzyme (ACE) inhibitors, and calcium channel blockers. The newer ACE inhibitors and calcium channel blockers were promoted as being better for the treatment of hypertension than the older thiazide diuretics and beta blockers, however this was mostly marketing hype since the newer drugs were on patent and made more money for the drug companies. However the studies showed that, at least compared to thiazide diuretics, the newer drugs weren't as good, even they cost much more.

Thiazide diuretic drugs work for hypertension by increasing urine output and decreasing the volume of fluid in your circulation, which they achieve by increasing sodium excretion from the kidney, which drags water along with it. Examples include hydrochlorothiazide (Esidrix, Hydrodiuril, Microzide) and chlorthalidone (Hygroton). Thiazides promote calcium retention and prevent bone loss and fractures. However, they can negatively interact with an extensive list of medications, which are listed in the Physicians Desk Reference.

Their main problem is that they cause is frequent urination, which is inconvenient to say the least. They can also be associated with a loss of potassium Low serum potassium, or hypokalemia, is a potentially fatal condition, that can be associated with symptoms of muscle weakness, confusion, dizziness that can lead to falls, and heart arrhythmias. For people with a healthy diet, this is not a problem. You can also possible to take potassium supplements by mouth every day, to avoid the problem of potassium depletion with diuretics. A sub-category of these drugs, the so-called thiazide-like diuretic indapamide (Lozol) can cause life-threatening drops of sodium in the blood. In 1992 the Australian authorities reported 164 cases of this potentially life threatening condition, which is associated with confusion, lethargy, nausea, vomiting, dizziness, loss of appetite, fatigue, fainting, sleepiness, and possible convulsions. Since it doesn't work better than hydrochlorothiazide, and is potentially dangerous, it should not be used.

ACE inhibitors are one of the newest types of hypertension drugs. They act on the renin-angiotensin system that regulates blood pressure and kidney function. Normally, the molecule angiotensin I is converted to angiotensin II by the angiotensin-converting enzyme. Angiotensin II is a potent vasoconstrictor that makes your blood vessels close down. By blocking the angiotensin-converting enzyme, you make the blood vessels relax, decreasing blood pressure. Examples of this type of drug include lisinopril (Prinivil), enalapril (Vasotec), ramipril (Altace), benazepril (Lotensin), fosinopril (Monopril), and captopril (Capoten). Side effects of ACE inhibitors include headache, flushing, diarrhea, rash, and more rarely dizziness, heart failure or stroke. One of the most annoying side effects is a dry persistent cough. Angiotensin receptor blockers (ARBs), like valsartan (Diovan), irbesartan (Avapro), olmesartan (Benicar), candesartan (Atacand), and losartan (Cozaar; Hyzaar when combined with hydrochlorothiazide) act on the angiotensin receptor to block its effects, thereby reducing blood pressure. Side effects include dizziness, diarrhea, rash, and more rarely anxiety, muscle pains, upper respiratory track infection, low blood pressure or elevations in potassium.

Calcium channel blockers act on the lining of the blood vessels. When these channels let calcium in, the blood vessels constrict. By blocking the calcium channels, these drugs cause the vessels to relax, as a result blood pressure goes down. Examples of this type of drug include amlodipine (Norvasc), verapamil (Calan), nifedipine (Procardia, Adalat), and diltiazem (Tiazac). Side effects include constipation, dizziness, headache, nausea, and more rarely low blood pressure, heart failure or arrhythmias.

Calcium channel blockers have not been found to prevent heart attacks better than diuretics (ALLHAT 2002; Black et al 2003; Brown et al 2000; Hansson et al 2000). In fact, one study showed that calcium channel blockers (nifedipine) did not prevent heart attacks or chest pain (angina) any better than a placebo, or sugar pill (Poole-Wilson et al 2004). A meta analysis of all studies combined showed that treatment with calcium channel blockers did not improve mortality more than a placebo, although ACE inhibitors did (BPLTTC. 2000). Another meta analysis found that treatment with calcium channel blockers when compared to other medication treatments for high blood pressure was associated with a relative 26% increase in heart attacks, 25% increase in heart failure, and 10% increase in major cardiovascular events (Pahor et al 2000). Furthermore, for women calcium channel blockers increased the risk of heart attack or stroke by 18% (Poole-Wilson et al 2004). Calcium channel blockers have been found to increase the risk of heart failure relative to other antihypertension drugs in several studies,(Black et al 2003; BPLTTC. 2000; Pahor et al 2000; Pepine et al 2003) overall by about 20% (BPLTTC 2003). In spite of this, one of the calcium channel blockers, amlodipine, continues to be a blockbuster drug, with 2 billion dollars a year in sales reported in 2003, a year after the troubling reports of heart failure with calcium channel blockers was published.

In the NIH-sponsored Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). In ALLHAT, the largest study of antihypertensive medications ever performed, different types of antihypertensive treatments were compared in 33,357 patients with high blood pressure and one other risk factor for heart disease were randomly assigned to the "old" drug chlorthalidone (diuretic), or the "new" drugs amlodipine (calcium channel blocker), or lisinopril (ACE inhibitor). Rates of fatal and nonfatal heart attacks were essentially the same between the three treatments (ALLHAT 2002). There was a 38% increase in heart failure with amlodipine compared to chlorthalidone. For lisinopril there were increased rates of total cardiovascular disease outcomes (10%), stroke (15%) and heart failure (19%) compared to chlorthalidone.

Since the time of ALLHAT other studies have not shown that ACE inhibitors and calcium channel blockers work better than diuretics, even though they cost more. And like ALLHAT, some of these studies show cause for concern.

As I mentioned above, many of the studies involved a comparison of "old" and "new" drugs, showing no difference in heart attacks and strokes for the two types of drugs. For the old drugs the studies often lumped together atenolol and a diuretic. However as I will explain later in more detail atenolol is probably not a very good drug, so these studies may have hid the fact that diuretics are better! In any case they show that there is no reason to spend more money on the new drugs. Follow along now while I spell out some of those studies.

For instance, in the NORdic DILtiazem (NORDIL) study, (Hansson et al 2000) which compared diltiazem (calcium channel blocker) to diuretics and/or beta blockers in 10,881 patients from Norway and Sweden, there were no differences in rates of fatal or non-fatal heart. Other studies which showed essentially identical rates of heart attack or stroke included The Controlled ONset Verapamil INvestigation of Cardiovascular End points (CONVINCE) Trial, a study of 16,602 patients who received verapamil (calcium channel blocker), or atenolol (beta blocker)/hydrochlorothiazide (diuretic) (Black et al 2003). The INternational VErapamil trandolapril STudy (INVEST), which compared the calcium channel blocker verapamil to the beta blocker atenolol in 22,576 patients (Pepine et al 2003). The Swedish Trial in Old Patients with Hypertension 2 (STOP-2) (Hansson et al 1999a) study, which randomised 6614 patients age 70-84 to either "new" drugs like calcium channel blockers or ACE inhibitors, or "old" drugs diuretics and beta blockers, and the CAptopril Prevention Project (CAPPP) as study of captopril (ACE inhibitor) versus diuretics and/or beta blocker in 10,985 patients (Hansson et al 1999b).

Not only was it difficult to show that the new drugs were better than the old (the marketing goal that drove the design of the studies), it wasn't easy to show that taking the drugs was better than doing nothing. For instance, in the ACTION Study (A Coronary disease Trial Investigating Outcome with Nifedipine), 7665 patients with stable angina received the calcium channel blocker nifedipine or placebo in a randomized trial (Poole-Wilson et al 2004). There was no difference in a combined measure of fatal and non-fatal heart attack or stroke, revascularization, or heart failure. Death from heart disease was equal in the groups, and there was a 16% increase in non-cardiac deaths with nifedipine that was not statistically significant. Women on nifedipine had an 18% increase in this measure of cardiac events, although the difference was not statistically significant. In the Heart Outcomes Prevention Evaluation (HOPE) Study, 9297 patients at high risk for heart disease were randomized to the ACE inhibitor ramipril or placebo in addition to their usual treatment (HOPE 2000). A fatal or non-fatal heart attack or stroke was seen in 14.0% of the ramipril patients compared to 17.8% on placebo, a difference that was statistically significant. In the Prevention of Events with Angiotensin Converting Enzyme Inhibition (PEACE) Trial, a study of 8290 patients with heart disease, the addition of the ACE inhibitor Trandolapril had no effect on reducing heart attacks and coronary revascularization procedures compared to a placebo (PEACE 2004). These results led to an editorial called "ACE inhibitors in Patients with Stable Heart Disease-may they rest in Peace?"

The Valsartan Antihypertensive Long term Use Evaluation (VALUE) study compared the ARB valsartan to the calcium channel blocker amlodipine in 15,245 patients over age 50 with high blood pressure and a high risk of heart disease (Julius et al 2004). The study found no difference between the two drugs in fatal and non-fatal heart attacks and other cardiac events. More non-fatal heart attacks were seen with valsartan, but there was also less development of diabetes. This study led to an editorial called "Is there Value in Value?"

When new drugs were compared to diuretics alone, their performance was worse. For instance, the Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS) compared the calcium channel blocker isradipine to the diuretic chlorthalidone in 883 patients with high blood pressure. Twenty five patients on isradipine had a major cardiovascular event (heart attack, stroke, heart failure, death or angina) compared to 14 on diuretic, a difference which was statistically significant (Borhani et al 1996). In the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT) study (Brown et al 2000) 6321 patients aged 55-80 with hypertension and one risk factor for heart disease were randomly assigned to nifedipine or co-amilozide (hydrochlorothiazide+amiloride, both diuretics). In the nifedipine group, 200 had cardiovascular death, heart attack, heart failure or stroke (combined) versus 182 in the diuretic group, which was not statistically significant. The nifedipine group did have significantly more fatal heart attacks (16 versus 5) and non-fatal heart failure (24 versus 11).

Dr. Bruce Psaty and colleagues from the University of Washington in Seattle looked at all of the data from trials that had been published up to 2003. Overall they found that diuretics were superior to all other treatments (Psaty et al 2003). Compared to placebo diuretics reduced the risk of heart disease by 21%, heart failure by 49%, stroke by 29% and total mortality by 10% (all significant). Diuretics compared to calcium channel blockers had 6% fewer cardiovascular disease events and 26% less heart failure; compared to ACE inhibitors there was 12% less heart failure, 6% less cardiovascular disease events and 14% less stroke. Diuretics compared to beta blockers had 11% less cardiovascular disease events. All treatments were similar in their ability to lower blood pressure. The authors concluded that diuretics (but not beta blockers, as was the recommendation at the time) should be the first line of treatment for high blood pressure.

Most of the studies of antihypertensive medications have been done in men. In the only study focused on women, 30,219 women with hypertension without heart disease were assessed for the relationship between anti-hypertensive therapy and outcome. Use of calcium channel blockers compared to diuretic was associated with a 55% increased risk of cardiovascular death, diuretic plus calcium channel blocker was associated with an 85% increased risk of cardiovascular death compared to diuretic plus beta-blocker. The risk increased to 2.16 when women with diabetes were excluded (Bhatt et al 2006; Wassertheil-Smoller et al 2004).

The alpha-blockers block the alpha noradrenergic receptor in the heart and blood vessels, and include doxazosin (Cardura), prazosin (Minipress) and terazosin (Hytrin). A related drug called Labetalol (Normodyne) blocks both alpha and beta-receptors. The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) Study showed that the alpha blocker Cardura doubled the risk of heart failure and increased the risk of stroke and all cardiovascular disease when compared to diuretic. This led to the study being stopped early; the authors of ALLHAT concluded that alpha-blockers should not be used in the treatment of hypertension (Davis 2000). Based on this I believe that there is no role for alpha-blockers in the treatment of patients with hypertension.

What is the bottom line for the treatment of hypertension? First things first. Cut sodium from your diet. That means making your own dinner whenever possible, since processed, canned and frozen foods are full of sodium, as food meals. Exercise by moderate walking for 30 minutes three times a week. Try stress reduction or meditation. Stop smoking. Do not drink alcohol in excessive amounts.

If these changes fail to lower your blood pressure, you may need medication. Work with your doctor to find out what works best for you. You may need to be started on the standard and least expensive treatment, diuretics. They work better than the newer drugs, based on the research I outlined earlier, and they have fewer side effects overall than the newer medications. This is especially true if you are African-American. You should definitely not take an ACE inhibitor or calcium channel blocker if you are not taking a diuretic.

Alpha-blockers should not be taken under any circumstances. These drugs seem to cause more heart problems than conventional diuretic treatments. Potassium sparing diuretics are dangerous and should be avoided.

If your blood pressure is not controlled with a diuretic, you may need to add another medication. This means going to a beta blocker, ACE inhibitor or calcium channel blocker. I do not recommend atenolol; you can use another beta blocker like metoprolol. Women should not take a calcium channel blocker. ACE inhibitors or ARB drugs can help whites with left ventricular (heart pump) failure.

ALLHAT (2002): Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). Journal of the American Medical Association 288:2981-2997.

Bhatt D, Fox KAa, Hacke W, et al (2006): Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. New England Journal of Medicine 354:1706-1717.

Black HR, Elliott WJ, Grandits G, et al (2003): Principal results of the Controlled Onset Verapamil Investigation of Cardiovascular End Points (CONVINCE) Trial. Journal of the American Medical Association 289:2073-2082.

Borhani N, Mercuir M, Borhani PA, et al (1996): Final outcome results of the Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS): A randomized controlled trial. Journal of the American Medical Association 276:785-791.

BPLTTC (2003): Blood Pressure Lowering Treatment Trialists' Collaboration. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. Lancet 362:1527-1535.

BPLTTC. (2000): Blood Pressure Lowering Treatment Trialists Collaboration. Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials. Lancet 355:1955-1964.

Brown MJ, Palmer CR, Castaigne A, et al (2000): Morbidity and mortality in patients randomised to double-blind treatment with long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT). Lancet 356:366-372.

Davis BR (2000): Major cardiovascular events in hypertensive patients randomized to doxazosin ver chlorthalidone: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). Journal of the American Medical Association 283:1967-1975.

Hansson L, Hedner T, Lund-Johansen P, et al (2000): Randomised trial of effects of calcium antagonists compared with diuretics and beta blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) study. Lancet 356:359-365.

Hansson L, Lindholm LH, Ekborn T, et al (1999a): Randomised trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 study. Lancet 354:1751-1756.

Hansson L, Lindholm LH, Niskanen L, et al (1999b): Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captropril Prevention Project (CAPPP) randomised trial. Lancet 353:611-616.

HOPE (2000): Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. New England Journal of Medicine 342:145-153.

Julius S, Kjeldsen SE, Weber B, et al (2004): Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 363:2022-2031.

Pahor M, Psaty BM, Alderman MH, et al (2000): Health outcomes associated with calcium antagonists compared with other first-line antihypertensive therapies: a meta-analysis of randomised controlled trials. Lancet 356:1949-1954.

PEACE (2004): The PEACE Trial Investigators. Angiotensin-Converting Enzyme inhibition in stable coronary artery disease. New England Journal of Medicine 351:2058-2068.

Pepine CJ, Handberg EM, Cooper-DeHoff RM, et al (2003): A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease: The International Verapamil-Trandolapril Study (INVEST): A randomized controlled trial. Journal of the American Medical Association 21:2805-2816.

Poole-Wilson PA, Lubsen J, Kirwan B-A, et al (2004): Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION): randomised controlled trial. Lancet 364:849-857.

Psaty BM, Lumley T, Furberg CD, et al (2003): Health outcomes associated with various antihypertensive therapies used as first-line agents: A network meta-analysis. Journal of the American Medical Association 289:2534-2544.

Wassertheil-Smoller S, Psaty B, Greenland P, et al (2004): Association between cardiovascular outcomes and antihypertension drug treatment in older women. Journal of the American Medical Association 292:2849-2859.

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